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学校：卡梅里诺大学 University of Camerino

院系：School of Pharmacy

教授：Prof. Roberto Ciccocioppo

申请网址：http://isas.unicam.it/2020-call-phd-applications 

截止日期：July 27, 2020

介绍

意大利卡梅里诺大学药学院的Roberto Ciccocioppo教授的实验室中现有两个博士生研读职位（3年）。

该实验室的研究主要集中在与人类心理病理相关的异常行为和脑功能异常的神经生物学基础研究上，重点在于药物成瘾和精神病学方面。大部分的工作旨在了解造成这些异常行为的神经机制，并确定新的药理学靶标以寻求新的更有效的治疗方法。同时该实验室也注重神经回路和分子机制的研究，从而对长期暴露于滥用或慢性压力药物有关的情绪和认知障碍进行有效控制

该实验室利用啮齿动物的自身给药试验来评估精神兴奋剂，阿片类药物和酒精所产生的激励效果和觅药的行为，同时利用分子生物学和免疫组化技术来评估细胞作用。该实验室还旨在使用光遗传学和DREADD技术探索神经回路范围内长期滥用药物的后果，并研究对动机行为和情绪调节所涉及的回路操纵如何调节滥用药物的寻找行为和反应行为。

我们正在寻找在体外电生理学或行为/分子药理学方面有丰富经验的，积极性高的候选人，从而扩大我们实验室的技术规模。 

要求

成功的候选人应具有：

• 脑外电生理学经验
  

• 免疫组化和病毒载体的使用
  

• 创新的思维能力，掌握神经科学文献
  

• 喜欢动物实验研究
  

• 有合作能力，优秀的沟通能力
  

• 英语熟练

  
  

申请

相关申请，请参阅（http://isas.unicam.it/2020-call-phd-applications）

Job description

Two PhD positions (3 years) are available in the laboratory of Prof. Roberto Ciccocioppo at the School of Pharmacy, University of Camerino, Italy. 

The research of our laboratory is mainly focused on the study of the neurobiological basis of abnormal behavioral and brain functions relevant to human psychopathology with emphasis on drug addiction and psychiatric disorders. The majority of this work is directed at the understanding the neurological mechanisms responsible for these aberrant behaviours and at identifying innovative pharmacological targets for new more effective treatments. Attention is also dedicated to the study of neurocircuitry and molecular mechanisms controlling emotional and cognitive disturbances associated with protracted exposure to drugs of abuse or chronic stress 

We utilise rodents self-administration assays to assess the motivational and drug-seeking effects of psychostimulats, opioids and alcohol, molecular biology and immunohistochemical techniques to assess cellular effects. We also aim to use optogenetic and DREADD technologies to explore at neurocircuitry level the consequence of protracted exposure to drugs of abuse and to study how manipulation of circuitries involved in the regulation of motivated behavior and emotion modulates seeking and taking responses for drugs of abuse.
We are seeking a highly motivated candidate with experience in in vitro electrophysiology or behavioral/molecular pharmacology to expand the technical abilities of our laboratory.